Determination of 1,4-Dioxane in Toluene by Gas Chromatography

✍ Scribed by Cortellucci, Remi ;Dietz, Edward A.

• Publisher: John Wiley and Sons
• Year: 1999
• Tongue: English
• Weight: 47 KB
• Volume: 22
• Category: Article
• ISSN: 0935-6304
• DOI: 10.1002/(sici)1521-4168(19990401)22:4<201::aid-jhrc201>3.0.co;2-i

✦ Synopsis

A gas chromatographic method is presented for determining from 1 to 100 lg/mL of 1,4-dioxane in toluene with purities ranging from commercial to high-purity grades. This method relies on extracting 1,4-dioxane from toluene into water. The water extract is analyzed for 1,4-dioxane content by gas chromatography/flame ionization detection and a capillary column coated with a bonded polyethylene glycol stationary phase. Splitless injection is used to achieve a 1 lg/ mL detection limit. Purging extracts with nitrogen after an initial analysis is suggested as an extract clean-up procedure and as a means to confirm the identification of 1,4-dioxane. However, for absolute identification of dioxane, gas chromatography/mass spectroscopy should be considered.