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Determination and pharmacokinetics of gastrodin and p-hydroxybenzylalcohol after oral administration of Gastrodia elata Bl. extract in rats by high-performance liquid chromatography–electrospray ionization mass spectrometric method

✍ Scribed by W. Zhang; Y.X. Sheng; J.L. Zhang

Book ID: 113848327
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 259 KB
Volume: 15
Category: Article
ISSN: 0944-7113
DOI: 10.1016/j.phymed.2008.02.012

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## Abstract A simple method using a one‐step liquid–liquid extraction (LLE) followed by high‐performance liquid chromatography (HPLC) with positive ion electrospray ionization tandem mass spectrometric (ESI‐MS/MS) detection was developed for the determination of bromazepam in human plasma, using lo