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Determinants of serum cotinine and hair cotinine as biomarkers of childhood secondhand smoke exposure

✍ Scribed by Kalkbrenner, Amy E; Hornung, Richard W; Bernert, John T; Hammond, S Katherine; Braun, Joe M; Lanphear, Bruce P

Book ID: 109871889
Publisher: Nature Publishing Group
Year: 2010
Tongue: English
Weight: 452 KB
Volume: 20
Category: Article
ISSN: 1559-0631
DOI: 10.1038/jes.2010.7

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## Abstract A simple liquid chromatography–electrospray ionization mass spectrometry (LC‐ESI‐MS) method for the determination of nicotine and cotinine in human hair was established. In the procedure, a hair sample (10 mg) was washed with dichloromethane and digested in 2.5 m sodium hydroxide. The d