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Determinants of Recombinant Production of Antimicrobial Cationic Peptides and Creation of Peptide Variants in Bacteria

✍ Scribed by L. Zhang; T. Falla; M. Wu; S. Fidai; J. Burian; W. Kay; R.E.W. Hancock


Book ID
115582282
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
226 KB
Volume
247
Category
Article
ISSN
0006-291X

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A fusion protein was genetically engineered that contains an antimicrobial peptide, designated P2, at its carboxy terminus and bovine prochymosin at its amino terminus. Bovine prochymosin was chosen as the fusion partner because of its complete insolubility in Escherichia coli, a property utilized t