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Determinants of drug response in a cisplatin-resistant human lung cancer cell line


Book ID
122974757
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
168 KB
Volume
7
Category
Article
ISSN
0169-5002

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Human lung cancer sublines resistant t o cisplatin (CDDP) have been developed by continuously exposing cells to gradually increasing doses of CDDP and use of the limiting dilution technique. The cell lines used were PC-7, PC-9 and PC-14 (pulmonary adenocarcinoma) and H69 and N23 I (small-cell lung c