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Determinants of Drug Disposition in Patients with Cirrhosis

✍ Scribed by Pierre-Michel Huet; Jean-Pierre Villeneuve


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
732 KB
Volume
3
Category
Article
ISSN
0270-9139

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Disposition kinetics and concentration-e
✍ I. JankΕ―; F. PerlΓ­k; M. TkaczykovΓ‘; M. BrodanovΓ‘ πŸ“‚ Article πŸ“… 1992 πŸ› Springer 🌐 English βš– 351 KB

The disposition kinetics and heart rate reducing effect of deacetylmetipranolol (DMP), the active form of the beta-adrenoreceptor blocking agent metipranolol (MP), administered as a single 40 mg oral dose have been compared in 6 patients with cirrhosis and 6 healthy volunteers. The mean maximal DMP