✦ LIBER ✦

Determinants of angiotensin II-induced hypertrophy versus hyperplasia in vascular smooth muscle

✍ Scribed by Gary K. Owens

Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 536 KB
Volume: 29
Category: Article
ISSN: 0272-4391
DOI: 10.1002/ddr.430290203

No coin nor oath required. For personal study only.

✦ Synopsis

There is clear evidence implicating a role for angiotensin II in control of hypertrophic growth of vascular smooth muscle cells in vivo. However, the specific mechanisms whereby angiotensin II influences smooth muscle cell growth have not been defined. The focus of this mini-review is to consider h o w angiotensin II contributes t o control o f hypertrophic vs. hyperplastic growth of vascular smooth muscle in vivo, and in particular how the differentiated state of the smooth muscle cell may influence growth responsiveness to angiotensin II.

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