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Deterioration in donepezil-induced PR prolongation after a coadministration of memantine in a patient with Alzheimer's disease

✍ Scribed by Igeta, Hirofumi; Suzuki, Yutaro; Motegi, Takaharu; Sasaki, Aiko; Yokoyama, Yuichi; Someya, Toshiyuki


Book ID
123378919
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
310 KB
Volume
35
Category
Article
ISSN
0163-8343

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Tolerability of switching from donepezil
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This study investigates the tolerability, safety and efficacy of abrupt or stepwise switching from donepezil to memantine treatment in patients with moderate-to-severe Alzheimer's disease (AD). Outpatients (Table 1), !50 years, with dementia of the Alzheimer's type (DSM-IV-TR), MMSE 18 and receiving