Detection ofPIK3CAmutations in circulating free DNA in patients with breast cancer
✍ Scribed by Ruth E. Board; Andrew M. Wardley; J. Michael Dixon; Anne C. Armstrong; Sacha Howell; Lorna Renshaw; Emma Donald; Alastair Greystoke; Malcolm Ranson; Andrew Hughes; Caroline Dive
- Publisher
- Springer US
- Year
- 2010
- Tongue
- English
- Weight
- 255 KB
- Volume
- 120
- Category
- Article
- ISSN
- 0167-6806
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Tumor cells are characterized by specific genetic alterations. When such genetic alterations are identified in body fluid including plasma, regardless of the presence of detectable tumor cells, it shows the existence of free‐circulating tumor‐associated DNA. The objective of our study w
## Abstract Interleukin‐6 (IL‐6) is a multifunctional cytokine produced by macrophages, T cells, B cells, endothelial cells and tumour cells. Interleukin‐6 is able to promote tumour growth by upregulating anti‐apoptotic and angiogenic proteins in tumour cells. In murine models it has been demonstra