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Detection of ΔF508 deletion by amplification refractory mutation system

✍ Scribed by Newton, C.R.; Schwarz, M.; Summers, C.; Heptinstall, L.E.; Graham, A.; Smith, J.C.; Super, M.; Markham, A.F.

Book ID
122768381
Publisher
The Lancet
Year
1990
Tongue
English
Weight
574 KB
Volume
335
Category
Article
ISSN
0140-6736

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In the present paper, we applied surface plasmon resonance (SPR) and biosensor technologies for biospecific interaction analysis (BIA) to detect DF508 mutation (F508del) of the cystic fibrosis transmembrane regulator (CFTR) gene in both homozygous as well as heterozygous human subjects. The proposed