## Abstract BALB/c mice were immunized with human melanoma cells and their spleen cells hybridized with NSβI myeloma cells. The hybrids were screened for the production of antibodies that bound to melanoma cells. Two hybridomas of interesting specificity were identified and cloned. Hybridoma 5.1 pr
Detection of tumor antigens with monoclonal antibodies: immunopathology and immunodiagnosis
β Scribed by A. Munro Neville
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 680 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0952-7915
No coin nor oath required. For personal study only.
β¦ Synopsis
The immunocytochemical demonstration, using monoclonal antibodies, of diverse cellular constituents has improved our understanding of many aspects of oncology. This review will focus on this approach to facilitate the detection of human tumors, improve their histological classification and provide functional parameters with potential aetiological, prognostic and/or therapeutic value.
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