Trophoblast cells can be detected in maternal blood during normal human pregnancy and DNA from these cells may be used for non-invasive prenatal diagnosis of inherited diseases. The possibility of enriching trophoblast cells from maternal blood samples using a monoclonal antibody (LK26) against a fo
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Detection of trophoblast cellular elements in maternal peripheral blood using monoclonal antibodies and flow cytometry
β Scribed by M. Adinolfi
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 155 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0196-4763
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Previous reports have shown, using fluorescent probes conjugated to the organism, that Mycoplasma fermentans fuses with about 12% of peripheral blood lymphocytes. However, no lymphocyte subset was specified. To elucidate the specific subset of lymphocytes involved, we developed a threecolor flow cyt