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Detection of the rapid emergence of the H275Y mutation associated with oseltamivir resistance in severe pandemic influenza virus A/H1N1 09 infections

✍ Scribed by Bin Wang; Dominic E. Dwyer; Christopher C. Blyth; Maly Soedjono; Haijing Shi; Alison Kesson; Mala Ratnamohan; Ken McPhie; Anthony L. Cunningham; Nitin K. Saksena


Book ID
113458384
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
800 KB
Volume
87
Category
Article
ISSN
0166-3542

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## Abstract Pandemic influenza A/H1N1 2009 (A/H1N1pdm) virus caused significant outbreaks worldwide last year (2009). A number of oseltamivir‐resistant A/H1N1pdm viruses possessing an H275Y substitution in the neuraminidase (NA) protein were reported sporadically in several countries, including Jap