Detection of the imbalance of procoagula
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Armando Tripodi; Massimo Primignani; Laura Lemma; Veena Chantarangkul; Alessandr
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Article
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2010
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John Wiley and Sons
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English
β 206 KB
Patients with cirrhosis possess an imbalance in procoagulant versus anticoagulant activity due to increased factor VIII and decreased protein C. This imbalance can be detected by thrombin-generation assays performed in the presence/absence of thrombomodulin (predicate assay) that are not readily ava