Detection of the negative-strand hepatitis C virus RNA in tissues: implications for pathogenesis
โ Scribed by Rafael Quadri; Laura Rubbia-Brandt; Karim Abid; Francesco Negro
- Book ID
- 114144357
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 162 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0166-3542
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The combination of reverse transcription and polymerase chain reaction is a very powerful tool for the detection of hepatitis C virus RNA in sera of patients with hepatitis C virus infection. However, when studying the presence of this virus in tissue using polymerase chain reaction, it may be diffi
The existence of extrahepatic reservoirs of hepatitis C virus (HCV) replication remains highly controversial. We searched for the presence of HCV-RNA negative strand in various tissues from eight HCV-infected patients who died of acquired immunodeficiency syndrome (AIDS)-related complications. Negat