Detection of the in vivo conversion of 2-pyrrolidinone to γ-aminobutyric acid in mouse brain
✍ Scribed by Patrick S. Callery; Martin Stogniew; Linda A. Geelhaar
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- English
- Weight
- 394 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1076-5174
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📜 SIMILAR VOLUMES
A'-Pyrroline is a putrescine metabolite that is biotransformed by rabbit liver preparations to 4-aminobutanoic acid and its lactam, 2-pyrrolidinone. Analysis of dilute aqueous solutions of A'-pyrroline by proton nuclear magnetic resonance indicated that the predominating species in the liver incubat
## ABSTRACT The concentration of brain __N__‐acetylaspartic acid (NAA) in mice was determined by high‐performance liquid chromatography (HPLC) using fluorescence detection after pre‐column derivatization with 4‐__N__,__N__‐dimethylaminosulfonyl‐7‐__N__‐(2‐aminoethyl)amino‐2,1,3‐benzoxadiazole (DBD‐