Detection of species specific epitopes of mouse and hamster prion proteins (PrPs) by anti-peptide antibodies

Epitope motif of an anti-nitrotyrosine a

Epitope motif of an anti-nitrotyrosine antibody specific for tyrosine-nitrated peptides revealed by a combination of affinity approaches and mass spectrometry

✍ Mihaela Drǎguşanu; Brînduşa-Alina Petre; Michael Przybylski 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 238 KB

## Abstract Nitration of tyrosine residues has been shown to be an important oxidative modification in proteins and has been suggested to play a role in several diseases such as atherosclerosis, asthma, lung and neurodegenerative diseases. Detection of nitrated proteins has been mainly based on the