Detection of single base substitutions in polynucleotides by capture with immobilized oligonucleotides
✍ Scribed by Patrick Balaguer; Béatrice Térouanne; Patrice Allibert; Philippe Cros; Anne-Marie Boussioux; Bernard Mandrand; Jean-Claude Nicolas
- Book ID
- 115637955
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 223 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0890-8508
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Recent advances in human genome research have revealed that genetic polymorphisms, such as single nucleotide polymorphisms (SNPs), are closely associated with susceptibility to various common diseases and adverse drug reactions. Also, numerous mutations responsible for a number of genetic diseases h
DNA microarray technology holds significant promise for human DNA diagnostics. A number of technical approaches directed at the parallel identification of mutations or single nucleotide polymorphisms make use of polymerase-based specificity, like minisequencing or allele-specific primer elongation.