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Detection of recurrent nasopharyngeal carcinomas with thallium-201 single-photon emission computed tomography in patients with indeterminate magnetic resonance imaging findings after radiotherapy

✍ Scribed by Chih-Jaan Tai; Ji-An Liang; Shih-Neng Yang; Ming-Hsui Tsai; Cheng-Chieh Lin; Chia-Hung Kao

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
118 KB
Volume
25
Category
Article
ISSN
1043-3074

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✦ Synopsis

Abstract

Background.

The aim of this study was to evaluate the usefulness of thallium‐201 (Tl‐201) single‐photon emission CT (SPECT) to detect recurrent nasopharyngeal carcinomas (NPC) when MRI findings are indeterminate.

Methods.

After radiotherapy, 26 NPC patients with indeterminate MRI findings were included in this study. MRI, Tl‐201, and biopsy were performed at least 4 months after radiotherapy and within 1 week. The final results were based on histopathologic findings and clinical follow‐up after at least 6 months.

Results.

For detecting recurrent NPC in indeterminate MRI findings, the sensitivity, specificity, and accuracy of Tl‐201 SPECT were 92.3%, 92.3%, and 92.3%, respectively.

Conclusions.

On the basis of this result, Tl‐201 SPECT seems to be effective in detecting recurrent NPC when MRI findings are indeterminate. Β© 2003 Wiley Periodicals, Inc. Head Neck 25: 227–231, 2003

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