Detection of receptor clustering by flow cytometric fluorescence anisotropy measurements

Flow cytometric measurement of low densi

Flow cytometric measurement of low density lipoprotein receptor activity validated by DNA analysis in diagnosing heterozygous familial hypercholesterolemia

✍ Petter Urdal; Trond P. Leren; Serena Tonstad; Per Kr Lund; Leiv Ose 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 51 KB 👁 2 views

We have evaluated whether low density lipoprotein (LDL) receptor activity of stimulated lymphocytes, as measured by an improved flow cytometric assay, may be used to diagnose familial hypercholesterolemia (FH). Cells were isolated from 75 children suspected from strict clinical criteria to be FH het