Detection of QTL for milk production traits in cattle by application of a specifically developed marker map of BTA6
✍ Scribed by Ch Kühn; G Freyer; R Weikard; T Goldammer; M Schwerin
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 153 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0268-9146
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✦ Synopsis
Interval mapping was carried out to identify quantitative trait loci (QTL) for milk production traits in five granddaughter design families of the German Holstein population. Fourteen randomly generated markers spanning the whole of BTA6 and six targeted microsatellite markers from BTA6q21–31 were included in the analysis. In one family a QTL with effects on milk fat yield and milk protein yield was mapped to the interval TGLA37‐FBN13 (3 c
m proximal to FBN13, lodscore 3 ·22) in the middle part of the chromosome. Although there are several reports about QTL with effects on milk production traits on BTA6 in the literature, a QTL with effects on milk fat and milk protein yield has not been previously described.
After initial indications of at least two QTL for milk production traits ( Kühn et al. 1996b
) located in the middle of BTA6, microsatellite markers specific for the region of interest were developed (
Weikard et al. 1997
). The addition of five informative markers in the region BM143‐CSN3 decreased the average marker interval from 12 ·5 c
m to 5 ·5 c
m and more than doubled the number of informative geno‐ types.