We used a reverse transcriptase-polymerase chain reaction method for squamous-cell carcinoma (SCC) antigen mRNA to detect circulating tumour cells in patients with carcinoma of the uterine cervix. The sensitivity of the method, as determined by cell spiking experiments, was 10 cultured A431 cells am
✦ LIBER ✦
Detection of proliferative cells in dysplasia, carcinoma in situ, and invasive carcinoma of the uterine cervix by monoclonal antibody against DNA polymerase α
✍ Scribed by Masafumi Mushika; Tadashi Miwa; Yozo Suzuoki; Kazuma Hayashi; Shigeo Masaki; Tsuguhiro Kaneda
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 664 KB
- Volume
- 61
- Category
- Article
- ISSN
- 0008-543X
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The cancer-associated epitope defined by the monoclonal antibody (MAb) 9H8 was shown to be closely related to the T antigen (Thornsen-Friedenreich antigen) by its sensitivity to 0-glycanase treatment of a mucin glycopeptide known to express this epitope. The reactivity with this glycopeptide increas