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Detection of parental mosaicism in Down syndrome

✍ Scribed by K. Méhes


Book ID
119456655
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
93 KB
Volume
92
Category
Article
ISSN
1097-6833

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## Abstract Down syndrome (DS) is the most common aneuploidy in liveborns with an estimated frequency of 1 in 650–1,000 births. Approximately 1–2% of all live‐born DS individuals have mosaicism. The correlation between the percentage of mosaicism and the severity of the phenotype in mosaic trisomy