Detection of nucleic acid hybridization using surface plasmon resonance
β Scribed by Terek Schwarz; Debra Yeung; Edward Hawkins; Paul Heaney; Alex McDougall
- Book ID
- 113271721
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 246 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0167-7799
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π SIMILAR VOLUMES
An affinity sensor based on Surface Plasmon Resonance (SPR) was used to detect nucleic acids. SPR is an optical technique that is able to detect small changes in the refractive index of the immediate vicinity of a metal surface. After a specific ampIification of DNA, achieved using the polymerase ch
Biotinylated oligonucleotide probes were immobilized to the gold sensor surface of the TISPR-1 miniature integrated surface plasmon resonance liquid sensor system for the purpose of detecting specific DNA hybridization. The immobilization of the oligonucleotide capture probes was carried out through