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Detection of muramyl dipeptide-sensing pathway defects in patients with Crohn's disease

✍ Scribed by Dr. David A. van Heel; Karen A. Hunt; Kathy King; Subrata Ghosh; Simon M. Gabe; Christopher G. Mathew; Alastair Forbes; Raymond J. Playford

Book ID
110087078
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
186 KB
Volume
12
Category
Article
ISSN
1078-0998

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## Background: Mutations in the gene encoding the nucleotide-binding oligomerization domain 2 (nod2) protein are associated with crohn's disease (cd), but the mechanism underlying this is not completely understood. to study the mechanism of cd resulting from nod2 mutations, we analyzed nod2-depende