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Detection of mRNA in Mammalian Cells with a Split Ribozyme Reporter

โœ Scribed by Sumitaka Hasegawa; Gayatri Gowrishankar; Jianghong Rao


Book ID
101819147
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
267 KB
Volume
7
Category
Article
ISSN
1439-4227

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## Background: Cell-based reporter assays, which rely on a reporter gene under the control of a regulated promoter, are widely used to screen chemical libraries for novel receptor ligands. here, we describe a reporter system that is based on ligand-induced dna recombination to express the reporter