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Detection of minimal residual disease after sex-mismatch bone marrow transplantation in chronic myelogenous leukemia by fluorescence in situ hybridization

✍ Scribed by Arnon Nagler; Shimon Slavin; Shai Yarkoni; M. Fejgin; Aliza Amiel


Book ID
119106191
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
385 KB
Volume
73
Category
Article
ISSN
0165-4608

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We studied the feasibility and the sensitivity of fluorescent in situ hybridization (FISH) using leukemic or host/donor-specific probes on flow-sorted cells to assess minimal residual disease (MRD) or chimerism in transplanted patients in complete remission. We first performed experimental models of