Immunocytochemical detection (ICC) of isolated tumor cells in bone marrow (BM) is currently the most established method for monitoring early dissemination in epithelial cancer. However, the low sample size that can practically be analyzed restricts the sensitivity and reliability of the ICC method.
β¦ LIBER β¦
Detection of micrometastases in peripheral blood by immunomagnetic cell separation in patients with breast cancer
β Scribed by A. Lebrecht; K. Bluemke; H. Taubert; U. Bilkenroth; H.J. Holzhausen; E. Ulbrich; H. Koelbl
- Book ID
- 114315609
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 197 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0960-9776
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## Abstract ## BACKGROUND The efficient detection and characterization of micrometastatic cells in the bone marrow of patients with breast carcinoma are of prognostic and therapeutic importance. The technique used must overcome the challenges that result from the small number of target cells (1 pe
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