Detection of latent thymidine kinase-deficient herpes simplex virus in trigeminal ganglia of mice using the polymerase chain reaction
β Scribed by Anette Friedrich; J. P. Kleim; K. E. Schneweis
- Publisher
- Springer Vienna
- Year
- 1990
- Tongue
- English
- Weight
- 520 KB
- Volume
- 113
- Category
- Article
- ISSN
- 1432-8798
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Herpes simplex virus type 1 (HSV-1) DNA was extracted from human trigeminal ganglia of 121 cadavers aged between 3 months and 94 years, and its PCR amplification was performed for the RL2 HSV-1 sequence using two pairs of primers. The HSV-1 DNA was detected in 74 of 121 patients (61%); 70/74 bilater
## Abstract Investigation of varicellaβzoster virus (VZV) is important epidemiologically, and determination of its prevalence rate in human trigeminal ganglia is important to provide surveillance data. To date, studies on VZV detection in trigeminal ganglia have used specimens obtained from a relat