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Detection of KRAS mutations in colorectal cancer by high-resolution melting analysis

โœ Scribed by Ma, E S K; Wong, C L P; Law, F B F; Chan, W-K; Siu, D


Book ID
121375752
Publisher
BMJ Publishing Group
Year
2009
Tongue
English
Weight
807 KB
Volume
62
Category
Article
ISSN
0021-9746

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Considerable effort has been invested in the development of sophisticated technologies enabling detection of clinically significant low-level tumor specific KRAS mutations. Coamplification at lower denaturation temperature-PCR (COLD-PCR) is a new form of PCR that selectively amplifies mutation-conta