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Detection of KRAS mutant alleles in circulating cell-free tumor DNA in colorectal cancer patients resistant to cetuximab

✍ Scribed by Del Re, Marzia; Ulivi, Paola; Passardi, Alessandro; Zoli, Wainer; Danesi, Romano; Amadori, Dino


Book ID
125404153
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
72 KB
Volume
5
Category
Article
ISSN
1878-5077

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## Abstract Tumor cells are characterized by specific genetic alterations. When such genetic alterations are identified in body fluid including plasma, regardless of the presence of detectable tumor cells, it shows the existence of free‐circulating tumor‐associated DNA. The objective of our study w