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Detection of Ki-ras mutations in endocervical adenocarcinomas by polymerase chain reaction

✍ Scribed by J. Koulos; T. Wright; M. Mitchell; R. Richart


Book ID
119054324
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
167 KB
Volume
45
Category
Article
ISSN
0090-8258

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Detection of a rare point mutation in Ki
✍ Grimmond, S. M. ;Raghavan, D. ;Russell, P. J. πŸ“‚ Article πŸ“… 1992 πŸ› Springer 🌐 English βš– 615 KB

This paper represents the first report of a codon 59 mutation in Ki-ras from a spontaneous human transitional cell carcinoma of the bladder. Point mutations have the potential to activate the ras genes if they occur in critical coding regions. These include the sequences of codons 12, 13, 59, 61 and