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Detection of K- ras mutation in saccharin-treated human cells

✍ Scribed by H. Suzuki; N. Suzuki


Book ID
113253162
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
85 KB
Volume
334
Category
Article
ISSN
0165-1161

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Fifty percent of human colon carcinomas contain activating mutations in the K-ras gene. However, whether these alterations in K-ras affect the function of Ras proteins in growth factor (GF) signal transduction is not known. Here we have characterized a previously defined human colon carcinoma cell m