Detection of integrated human papillomavirus by human papillomavirus types 16 and 18 in situ hybridization: a valuable diagnostic tool in diagnosing cervical carcinoma?
โ Scribed by R.J.T. van Golde; J.A. de Hullu; R.L.M. Bekkers; J. Bulten; J.M.M. Grefte
- Book ID
- 113433973
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 444 KB
- Volume
- 199
- Category
- Article
- ISSN
- 1097-6868
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A total of six cervical carcinoma cell lines, of which two contained human papillomavirus (HPV) type 16 and four contained HPV type 18 DNA, were examined for viral RNA expression by spot-blot hybridization. All six cell lines contained HPV-specific cytoplasmic poly(A)-containing RNA. The same RNA sp
## BACKGROUND. The correlation between human papillomavirus (HPV) infection and tumor prognosis in 159 Russian women with cervical carcinoma was investigated. The presence of various HPV types was correlated with the histologic parameters of the carcinomas and with their immunoreactivity with anti