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Detection of in vitro culture-induced instability through inter-simple sequence repeat analysis

✍ Scribed by X. J. Leroy; K. Leon; J.M. Hily; P. Chaumeil; M. Branchard


Publisher
Springer
Year
2001
Tongue
English
Weight
138 KB
Volume
102
Category
Article
ISSN
0040-5752

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Genomic instability plays a major role in cancer by facilitating tumor progression and tumor heterogeneity. Inter-simple sequence repeat (inter-SSR) PCR has been developed to provide a rapid and reproducible technique for quantitation of the major type of genomic instability observed in sporadic tum