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Detection of immune complexes in experimental allergic neuritis

โœ Scribed by Chang-Sung Koh; Takeshi Nakano; Naoyuki Tsukada; Nabuo Yanagisawa; Akira Okano; Tamotsu Taketomi


Book ID
118929958
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
874 KB
Volume
63
Category
Article
ISSN
0022-510X

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We examined the evolution of demyelination in spinal roots of Lewis rats immunized with whole nerve and complete Freund's adjuvant. Roots were morphologically normal until 11 days after immunization, when we found endoneurial edema and myelin vesiculation in the absence of mononuclear cell contacts.