✦ LIBER ✦

Detection of humoral antibody to the transmissible venereal tumour of the dog

✍ Scribed by Dan Cohen

Publisher: John Wiley and Sons
Year: 1972
Tongue: French
Weight: 406 KB
Volume: 10
Category: Article
ISSN: 0020-7136
DOI: 10.1002/ijc.2910100126

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✦ Synopsis

Abstract

Humoral antibody against membrane‐associated antigens of the transmissible venereal tumour (TVT) of the dog was demonstrated using the indirect membrane immunofluorescence test. Circulating antibody to the tumour, as well as in vivo coating of the tumour cells with antibody, could be detected at 40 days or more after transplantation. Anti‐TVT activity was contained in the 19S, intermediate S and the 7S fractions of an anti‐TVT serum. No activity was detected in the 3.5S fraction. A cross‐reaction was demonstrated between anti‐TVT sera of clinical cases occurring in Ireland and Malaya.

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