Kaposi's sarcoma (KS) is a malignancy suspected of having an infectious etiology. Unique viral DNA sequences were recognized in KS lesions, using a novel technique that identifies small differences between two complex genomes. The virus had homology with the herpesvirus family, especially Epstein Ba
Detection of human herpesvirus-8 DNA in Kaposi’s sarcomas from iatrogenically immunosuppressed patients
✍ Scribed by Peter L. Rady; Emmilia Hodak; Angela Yen; Omeed Memar; Akiva Trattner; Meora Feinmesser; Michael David; S.David Hudnall; Stephen K. Tyring
- Book ID
- 117396555
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 250 KB
- Volume
- 38
- Category
- Article
- ISSN
- 1097-6787
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The identification of Kaposi's sarcoma (KS) clusters in subequatorial Africa (endemic KS, AKS) and the high frequency of KS in sexually transmitted AIDS (epidemic KS, EKS), have previously suggested a role for infectious agents in the etiopathogenesis of KS. The recent identification of herpesvirus
## Abstract We report the molecular characterization of 38 new Kaposi's sarcoma‐associated herpesvirus (KSHV) strains from Russian patients with either classic (25 cases), epidemic/AIDS‐associated (7 cases), or posttransplant/immunosuppressed patients (6 cases), or Kaposi's sarcoma (KS). While a co