A PCR assay using capillary electrophoresis was designed for the detection of c-erbB-2 gene amplification in alcoholformalin-acetic acid (AFA)-fixed, paraffin-embedded biopsies from 81 consecutive breast tumors. c-erbB-2 expression was analyzed in the same samples using immuno-histochemistry (IHC).
✦ LIBER ✦
Detection of HER-2/neu gene amplification in breast carcinomas using quantitative real-time PCR — A comparison with immunohistochemical and FISH results
✍ Scribed by Janina Kulka; Anna-Mária Tokés; Pál Kaposi-Novák; Nóra Udvarhelyi; Anikó Keller; Gábor Lotz; Zsuzsa Schaff
- Publisher
- Springer Netherlands
- Year
- 2006
- Tongue
- English
- Weight
- 388 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1219-4956
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## Abstract ## BACKGROUND The objective of this article was to compare five tumor markers between white women in the U.S. and native Korean women with early‐onset breast carcinoma. ## METHODS Sixty Korean women who were diagnosed with breast carcinoma at age 45 years or younger and 60 white wome