The core promoter region of hepatitis B virus genomes regulates transcription of the precore and pregenomic mRNAs encoding hepatitis B e antigen (HBeAg) and core antigen that contain target epitopes for cytotoxic T lymphocytes. The prevalence and clinical significance of mutations in this region wer
✦ LIBER ✦
Detection of hepatitis B virus X gene and PreC promoter mutations from chronic hepatitis B patients in the south of Turkey
✍ Scribed by Aylin Dogen, Engin Kaplan, Mehmet Sami Serin…
- Book ID
- 120894743
- Publisher
- Allerton Press, Inc.
- Year
- 2013
- Tongue
- English
- Weight
- 336 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0891-4168
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## Abstract The association of precore stop codon mutation (A1896), dinucleotide mutation (T1762/A1764) in the basic core promoter of hepatitis B virus (HBV) genome, and genotype of HBV with fulminant or subfulminant hepatitis remains controversial. We studied HBV genotypes as well as mutations in
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