Detection of glucose at a rotating gold composite electrode by pulsed amperometric detection

✍ Scribed by Peter T. Elliott; Scott A. Olsen; Dennis E. Tallman

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 482 KB
• Volume: 8
• Category: Article
• ISSN: 1040-0397
• DOI: 10.1002/elan.1140080508

✦ Synopsis

Abstract

Segregated composite electrodes mimic microelectrode ensembles. In this preliminary report, the use of a rotating gold‐polychlorotri‐ fluoroethylene (or Kel‐F, a 3M Company polymer) composite electrode in combination with pulsed amperometric detection (PAD) is described for the detection of glucose. Comparisons are made with results obtained at a solid gold disk electrode. The composite electrode exhibits a higher signal and a lower background than does the solid gold electrode. In terms of current density, the enhancement of the signal above the background is over 3‐fold, similar to that observed with segregated graphite composite electrodes used in a constant potential mode. Little or no glucose signal is observed at either the solid gold or the gold composite electrode when employed in the constant potential mode. In the PAD mode, the signal is stable for periods in excess of an hour.