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Detection of Giant Myofibrillar Proteins Connectin and Nebulin by Electrophoresis in 2% Polyacrylamide Slab Gels Strengthened with Agarose

✍ Scribed by R. Tatsumi; A. Hattori


Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
422 KB
Volume
224
Category
Article
ISSN
0003-2697

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✦ Synopsis


We have established an improved method of sodium dodecyl sulfate-polyacrylamide gel electrophoresis to facilitate analysis of giant myofibrillar proteins connectin and nebulin, whose molecular masses are about 3000 and (700 \mathrm{kDa}), respectively. This method consists of (2 %) polyacrylamide slab gels strengthened with agarose and a specific buffer system. Our (2 %) polyacrylamide slab gels are superior to usual 1.8 or (2 %) polyacrylamide disc gels in preparation, handling, and resolution. 1995 Academic Press, Inc.