Detection of free radicals during reperfusion injury in dog heart
β Scribed by S. Itoh; T. Yanagishita; M. Tomita; S. Mukae; K. Umetsu; E. Geshi; N. Konno; S. Koba; H. Suzuki; T. Katagiri; H. Utsumi; A. Hamada
- Book ID
- 115983381
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 106 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0022-2828
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π SIMILAR VOLUMES
## Abstract By use of an optimized cytochrome cβbased biosensor, superoxide radical production was measured continuously in vivo. The aim of this study was the online detection of superoxide concentration during reperfusion after a variable time of ischemia. Measurements were performed by placing t
Several studies indicate the presence of hydroxyl radical (OH.) as well as its involvement in the myocardial reperfusion injury. A transition metal-like iron is necessary for the conversion of superoxide anion (O2-) to a highly reactive and cytotoxic hydroxyl radical (OH.). In the present study, we