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Detection of ETV6 and RUNX1 gene rearrangements using fluorescence in situ hybridization in Mexican patients with acute lymphoblastic leukemia: experience at a single institution

✍ Scribed by Patricia Pérez-Vera; Oreth Montero-Ruiz; Sara Frías; Verónica Ulloa-Avilés; Rocío Cárdenas-Cardós; Rogelio Paredes-Aguilera; Roberto Rivera-Luna; Alessandra Carnevale


Book ID
113512711
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
151 KB
Volume
162
Category
Article
ISSN
0165-4608

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## Abstract In childhood B‐lineage acute lymphoblastic leukemia (ALL), the most common genetic change, the __ETV6‐CBFA2__ (__TEL‐AML1__) fusion resulting from the cryptic t(12;21)(p13;q22) is associated with a favorable outcome. Therefore, it is important to identify patients with this translocatio