Detection of Epstein-Barr virus in Korean peripheral T-cell lymphoma
โ Scribed by Jooryung Huh; Kwanghyun Cho; Dae Seog Heo; Ji Eun Kim; Chul Woo Kim
- Book ID
- 119977105
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 389 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0361-8609
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Although Epstein-Barr virus (EBV) positivity has been described in peripheral T-cell lymphomas (PTCLs) in Chinese patients, the cellular lineage of EBV-harbouring cells is unknown. Forty-four cases of PTCL were therefore studied by in situ hybridization (ISH) for EBV-encoded small non-polyadenylated
terminal hemophagocytosis syndrome. All five relapsed tumors were found to have a strong expression of P-glycoprotein (P-gp). Conclusions. The authors suggest that EBV-associated PTCL should be regarded as a separate entity of non-Hodgkin lymphoma showing characteristic histopathologic features, fr