✦ LIBER ✦
Detection of Epstein-Barr viral DNA internal repeats in the nasopharyngeal mucosa of chinese with IgA/ebv-specific antibodies
✍ Scribed by C. Desgranges; G. W. Bornkamm; Y. Zeng; P. C. Wang; J. S. Zhu; M. Shang; G. De-Thé
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- French
- Weight
- 246 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0020-7136
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✦ Synopsis
Abstract
Fifty‐six South Chinese individuals exhibiting IgA antibodies to EBV for 18 months and presenting naso‐pharyngeal abnormalities were biopsied. Four nasopha‐ryngeal carcinomas, two at a very early stage, were detected. In 14 further individuals, without clinical or his‐topathological evidence of tumor, EBV/DNA internal repeats and/or EBNA were detected in the biopsied mucosae. The presence of IgA/EBV antibodies and/or EBV markers in the nasopharyngeal mucosa may characterize pre‐cancerous conditions.