Detection of RNA Hybridization by Pyrene
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Guojie Wang; Georgii V. Bobkov; Sergey N. Mikhailov; Guy Schepers; Arthur Van Ae
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Article
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2009
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John Wiley and Sons
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English
β 847 KB
## Abstract **Powerful pyrene probes**: Two kinds of pyreneβlabeled oligonucleotides (HNAβ and RNAβskeleton probes) were explored. The enhanced fluorescence intensity in the monomer region and the disappearance of aggregate/excimer emission in duplexes has been successfully used to detect the hybri