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Detection of differential gene copy number using denaturing high performance liquid chromatography

✍ Scribed by Jitender Kumar; Arun Kumar; Swapan Kumar Das; Garima Shukla; Shantanu Sengupta


Book ID
113681738
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
212 KB
Volume
64
Category
Article
ISSN
0165-022X

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## Communicated by Riccardo Fodde Microsatellite instability (MSI) is a hallmark of the DNA replication error phenotype, due to the inactivation of mismatch repair genes. MSI has been implicated in colon and many other gastrointestinal cancers. MSI usually can be analyzed by PCR amplification of m