Based on sequence variation of the glycoprotein B (gB) gene, human cytomegalovirus (HCMV) strains can be classified into four gB genotypes. In a previous study of bone marrow transplant recipients, infection with the gB type 1 correlated with a more favorable clinical outcome than infection with the
Detection of cytomegalovirus-specific igm in renal transplant recipients
β Scribed by Cheryl A. McMahon; Ellyn B. Lentz; Nancy L. Dock; Harold V. Lamberson; Betty A. Forbes; Nancy L. Dock; Harold V. Lamberson; Emanuel R. Reinitz
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 514 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0887-8013
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The value of IgM detection for the early diagnosis of an active cytomegalovirus (CMV) infection in renal transplant recipients was evaluated prospectively. Sequential serum samples obtained from 22 allograft recipients with active CMV infection were tested for the presence of CMV-specific immunoglob
## Abstract Although most genes are highly conserved among strains of human cytomegalovirus (HCMV), several are unusually variable. By analyzing the sequence of two variable genes (__UL146__ and __UL74__) amplified directly from whole blood DNA extracts, multiple HCMV strains were detected in blood
## Abstract Whether valaciclovir (VCV) prophylaxis could be responsible for ganciclovir (GCV)βresistance of __Human cytomegalovirus__ (HCMV) in transplantation has never been documented. A multicentric retrospective pilot study was undertaken to detect GCVβresistance through mutations within the __
The sources of cytomegalovirus (CMV) infection in seropositive renal transplant recipients include reactivation of latent endogenous virus in the recipient, reactivation of latent virus in donated kidney, or both. If infection occurs by either source, viruses isolated from the same recipient should
## Background: Cytomegalovirus (cmv) infection is a common opportunistic pathogen in transplant recipients; however, cytomegaloviral laryngitis is extremely rare. ## Methods: We present a case of disseminated cmv infection and ulcerating necrotizing laryngitis situated in the subglottis of an imm