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Detection of cross-reacting epitopes on plasmid-encoded outer membrane proteins of enteropathogenicYersiniaby monoclonal antibodies

✍ Scribed by Jürgen Weninger; Christoph Schoerner; Klaus Wartenberg; Martin Röllinghoff

Publisher: Springer-Verlag
Year: 1989
Tongue: English
Weight: 536 KB
Volume: 178
Category: Article
ISSN: 0300-8584
DOI: 10.1007/bf00202291

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✦ Synopsis

Plasmid-positive Yersinia bacteria of different species and different serotypes were analysed with respect to the immunological relationship of two of their plasmid-encoded outer membrane proteins (OMPs) by the immunoblot technique using three monoclonal antibodies (mAb), which were induced against OMPs of Yersinia enterocolitica serotype O:9 bacteria. Evidence is presented that these OMPs display discrete epitopes, which are common to all plasmid-positive Yersinia strains tested, with only one exception, indicating a close structural relationship of the OMPs analysed.

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